ORIFICE

noun
12 Scrabble
13 WWF
O 1
R 1
I 1
F 4
I 1
C 3
E 1

Definition

A mouth or aperture, such as of a tube, pipe, etc.; an opening.

"the orifice of an artery or vein;   the orifice of a wound;   the vagina and other orifices"

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